Intrauterine Insemination (IUI) is a fertility treatment in which processed sperm is placed directly into the uterus around the time of ovulation. This increases the chances of fertilization by bringing sperm closer to the egg, offering a less invasive and cost-effective solution compared to IVF.
When is IUI Recommended?
Mild endometriosis
PCOS/PCOD and ovulation problems
Mild male infertility
Sexually transmitted infections (STDs/STIs)
Genetic factors
Sexual dysfunction
Age-related infertility
Cervical issues
Stages of IUI Treatment
Day 1–5: Treatment begins with a baseline transvaginal scan.
Ovulation Induction: Hormonal tablets or injections are given to stimulate egg growth.
Follicular Monitoring: Ultrasound scans track follicle growth and egg maturity.
Sperm Preparation: The semen sample is washed and processed to isolate healthy, motile sperm.
Insemination: Around day 12–18, during ovulation, prepared sperm is placed directly into the uterus.
Success Rate: IUI typically has a success rate of 15–20% per cycle, depending on case selection.
Precautions During IUI Treatment
Take all prescribed medications as directed
Attend routine health check-ups and monitoring scans
Follow a balanced and nutritious diet
Avoid smoking, alcohol, and addictive substances
When to Consider Ovulation Induction with IUI?
Ovulation induction may be combined with IUI in cases of irregular or absent ovulation, or in unexplained infertility. This increases the chances of successful conception.
Success Rate: IUI with ovulation induction offers a success rate of around 20–25% per cycle.
Benefits of IUI Treatment
Less invasive compared to IVF
Mimics natural conception
Cost-effective and affordable
Quick procedure with minimal recovery
Helps in mild male infertility by improving chances with processed sperm
Donor sperm option available for single women or male infertility cases
Possible Side Effects and Considerations
While generally safe, IUI may cause mild side effects due to medications such as bloating, nausea, or water retention. Rarely, ovarian hyperstimulation syndrome (OHSS) or multiple pregnancies may occur if ovulation is overstimulated.
It is important to note that IUI requires confirmed ovulation, at least one healthy fallopian tube, and good-quality sperm for success. If donor sperm is used, the baby’s genetic traits will come from the donor, not the legal father, so proper donor selection is crucial.
